Details of Element: Creatinine Excretion (Mg Per 24 Hr)
Component of Body Composition

Unique Name: cempq
Contained in the Common BLSA Data Set ? No

Data Points (as of 09/06/98) Males Females Total
Number of Data Points 7154 872 8026
Number of Distinct Participants 1280 512 1792
Year First Collected 1958 1978 -
Year Last Collected 1988 1987 -

Type of Variable: Absolute Measure
Encoding: Continuous
Units of Measure: mg/24 hrs
Precision: ####.
Anticipated Range: 0700. thru 2500.
Masterfile Index: 161-01-33
Related Data Elements: none
Specific to this Data Element:
    Descriptive history:
    Creatinine excretion was measured in BLSA men from 1958 to 1987 and in BLSA women from 1978 to 1984. A colorometric method was used to assess the creatinine concentration in an aliquot of the 24 hour urine collection. Creatinine excretion is a marker for muscle mass and is also use to determine creatinine clearance. The renal clearance of endogenous creatinine is used as a measure of glomerular filtration rate.

    Data collection methodology:
    24 hour urine, colorometric analysis

    Related protocols:
    Body composition

    Investigators:
    Dr. Reubin Andres (primary investigator)
    GRC Box-24
    andresr@grc.nia.nih.gov
    (410)-558-8194

    Frequency of data collection:
    Selected visits.

    Inclusion/exclusion rules:
    None.

    Publications using these data:
  • Rowe J; Andres R; Tobin J et al.: The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. Journal of Gerontology 1976 31: 155-163 (1976).
  • Tzankoff SP; Norris AH: Effect of muscle mass decrease on age-related BMR changes. Journal of Applied Physiology 1977 43: 1001-1006 (1977).
  • Tzankoff SP; Norris A, H.: Longitudinal Changes in Basal Metabolism in Man. Journal of Applied Physiology 1978 45: 536-539 (1978).
  • Muller DC; Elahi D; Sorkin JD et al.: Muscle mass: Its measurement and influence on aging. The Baltimore Longitudinal Study of Aging.; in Rosenberg I, Nutritional Assessment of Elderly Populations: Measure and Function (New York, Raven Press 1995).
Details for this Data Type
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Revised 09/18/98 -- Send comments to our Web Master .