Details of Element: Sample 2
Component of Oral Glucose Test

Unique Name: sam2q32
Contained in the Common BLSA Data Set ? No

Data Points (as of 09/06/98) Males Females Total
Number of Data Points 3685 2394 6079
Number of Distinct Participants 1071 855 1926
Year First Collected 1958 1978 -
Year Last Collected 1998 1998 -

Type of Variable: Absolute Measure
Encoding: Continuous
Units of Measure: mg/dL
Precision: ###.
Anticipated Range: 000. thru 999.
Masterfile Index: 130-02-04
Related Data Elements: none
Specific to this Data Element:
    Descriptive history:
    The 130 file type contains data from the oral glucose tolerance test (OGTT). The oral glucose dose is 40 g per square meter of body surface area.. It consisted of a 25% solution flavored with lemon juice and is ingested in 5 minutes. The tests were performed between July 1977 and the present in BLSA men and women.

    Data collection methodology:
    Blood chemistry.

    Related protocols:
    Other blood chemistries.

    Investigators:
    Dr. Reubin Andres (primary investigator)
    GRC Box-24
    andresr@grc.nia.nih.gov
    (410)-558-8194

    Frequency of data collection:
    Every fourth or fifth visit.

    Inclusion/exclusion rules:
    No subjects previously diagnosed with Diabetes Mellitus.

    Publications using these data:
  • Andres, R. Aging, diabetes, and obesity: standards of normality. Mt Sinai J Med. 48(6): 489-95,1981.
  • Andres, R. Problems in the study of human aging. In: Schimke R, ed. Biological Mechanisms in Aging. Washington, D.C.: US Department of Health and Human Services, NIH Publication No. 81-2194, US Government Printing Office; 1981:696-700.
  • Goldberg, A., Andres, R., Bierman, E. Diabetes mellitus in the elderly. In: Andres R, Hazzard W, Bierman E, eds. Principles of Geriatric Medicine. New York: McGraw-Hill; 1985:750-763.
  • Potter, J.F., Levin, P., Anderson, R.A., Freiberg, J.M., Andres, R., Elahi, D. Glucose metabolism in glucose-intolerant older people during chromium supplementation. Metabolism. 34(3): 199-204,1985.
  • Andres, R. Diabetes mellitus in the elderly. In: Hazzard W, Andres R, Bierman E, Blass J, eds. Principles of Geriatric Medicine and Gerontology. 2nd ed. New York: McGraw-Hill; 1990:739-758.
  • Shimokata, H., Muller, D.C., Fleg, J.L., Sorkin, J., Ziemba, A.W., Andres, R. Age as independent determinant of glucose tolerance. Diabetes. 40(1): 44-51,1991.
  • Busby, M.J., Bellantoni, M.F., Tobin, J.D., Muller, D.C., Kafonek, S.D., Blackman, M.R., Andres, R. Glucose tolerance in women: the effects of age, body composition, and sex hormones. J Am Geriatr Soc. 40(5): 497-502,1992.
  • Andres, R. Diabetes and aging. In: Brocklehurst J, Tallis R, Fillit H, eds. Textbook of Geriatric Medicine and Gerontology. 4th ed. Edinburgh: Churchill Livingstone; 1992:724-728.
  • Elahi, D., Muller, D.C., McAloon-Dyke, M., Tobin, J.D., Andres, R. The effect of age on insulin response and glucose utilization during four hyperglycemic plateaus. Exp Gerontol. 28(4-5): 393-409,1993.
  • Muller, D.C., Elahi, D., Pratley, R.E., Tobin, J.D., Andres, R. An epidemiological test of the hyperinsulinemia-hypertension hypothesis. J Clin Endocrinol Metab. 76(3): 544-8,1993.
  • Muller, D., Elahi, D., Tobin, J., Andres, R. Insulin response during the oral glucose tolerance test: the role of age, sex, body fat and the pattern of fat distribution. Aging Clin. Exp. Res. 8: 13-21,1996.
Details for this Data Type
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