Details of Element: Low Density Lipoproteins (Ldl)
Component of Medical Laboratory

Unique Name: lodel
Contained in the Common BLSA Data Set ? Yes

Data Points (as of 09/06/98) Males Females Total
Number of Data Points 2402 1519 3921
Number of Distinct Participants 868 563 1431
Year First Collected 1974 1983 -
Year Last Collected 1992 1992 -

Type of Variable: Absolute Measure
Encoding: Continuous
Units of Measure: mg/dl
Precision: ###.
Anticipated Range: 000. thru 999.
Masterfile Index: 002-04-32
Related Data Elements: none
Specific to this Data Element:

    Descriptive History:
    Low density lipoproteins (also know as LDL-cholesterols) are computed from the Freidwald equation based on concentrations of cholesterol, triglyceride and high density lipoprotein. LDL-cholesterols have been entered continuously since 1983. During this time, different methods have been used to provide the LDL-cholesterol values. low density lipoprotein (ldl)' refers to computations made at the GRC (see description of calculated ccx low density liporotein' -- file 002, card 4). From 1983 to 1992 low density lipoproteins' were measured on the Abbott ABA-200 analyzer. From 1982 to 1987 values were obtained from serum and from 1987 to 1992 plasma samples were used.

    N.B. -- from 1991 to the present, LDL-cholesterol levels have been calculated from plasma using Abbott-CCX analyzer (see calculated ccx low density lipoprotein'-- file 002, card4)

    LDL-cholesterol (see above) measured in different sample types and with different methodologies are not equivalent. The low density lipoprotein' values in this file are entered as is. Longitudinal and cross-sectional analyses made over time periods where changes occurred in the methodology require adjustment to achieve consistancy (for more information please contact investigators).

    Data collection methodology:
    Blood chemistry.

    Related protocols:
    Other blood chemistries.

    Investigators:
    Dr. Reubin Andres (primary investigator)
    GRC Box-24
    andresr@grc.nia.nih.gov
    (410)-558-8194

    Frequency of data collection:
    Every visit.

    Inclusion/exclusion rules:
    None. Publications using these data:
  • Hallfrisch, J., Singh, V.N., Muller, D.C., Baldwin, H., Bannon, M.E., Andres, R. High plasma vitamin C associated with high plasma HDL- and HDL2 cholesterol. Am J Clin Nutr. 60(1): 100-5,1994.
Details for this Data Type
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